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by admin19.11.2015
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Почему же система «собственной безопасности» организма оборачивается против него самого? Потому что ее сформировали совсем другие условия жизни. И теперь, как сверхчувствительная пожарная сигнализация, она реагирует не только на дым от горящего ковра, но и на чад, поднимающийся над кухонной сковородкой и даже на пар от утреннего душа.

В результате может возникнуть от избытка висцерального жира, чересчур калорийной пищи, гиподинамии и, возможно, даже от повседневных стрессов. Никуда не исчезли из нашей жизни вялотекущие инфекции, например десен или околоносовых пазух, а аллергия вообще превратилась в настоящую эпидемию.

Кроме того, люди доживают до все более преклонных лет, а значит, их ткани дольше подвергаются воздействию воспалительных агентов и сильнее ими ослабляются. Вот лишь некоторые детали.

Индукторы воспаления

Враги здоровья

  • «Фаст-фуд» прочно вошел в нашу жизнь со своими высококалорийными, но малопитательными лакомствами. В эксперименте, проведенном Университетом штата Нью-Йорк в Буффало, завтрак из омлета с колбасой на английской пышке с картофелем фри (всего 910 ккал) наполнил кровь добровольцев вредными для артерий индикаторами воспаления. Их уровень оставался высоким в течение следующих 3 часов. Ученые считают, что регулярное потребление «фаст-фудов» вполне может держать организм в хронически воспаленном состоянии.
  • Висцеральный жир. Опять этот внутренний враг. Современная наука считает жировые клетки «гормональными насосами». Среди веществ, закачиваемых ими в кровь, цитокины, разнообразные белки, запускающие и координирующие воспалительную реакцию.
  • Окисленные лпнп. Свободные радикалы, окисляя этот «плохой» холестерин, повышают его способность проникать в стенки артерий. В ответ там начинается воспалительный процесс, способствующий образованию атеросклеротических бляшек, заполненных, среди прочего, иммунными клетками и продуктами тканевого распада.

Постепенно воспаление разъедает барьер, отделяющий все это от кровотока. Процесс идет с разной скоростью, причем самые «горячие» бляшки необязательно самые крупные, но обычно они прорываются первыми, что запускает внутрисосудистое свертывание крови (тромбоз), чреватый закупоркой артерий, т. е. инфарктом миокарда и ишемическим инсультом.

Индукторы воспаления

Вялотекущая инфекция.

Слабый грипп, бронхит, простой герпес, гингивит, хламидии и геликобактер (ответственный за большинство случаев язвы желудка) вызывают хроническое воспаление, заполняя кровь его агентами. Многие из нас, сами того не сознавая, постоянно живут с этими практически бессимптомными патологиями. Это открытие привело кардиологов к использованию для профилактики сердечной ишемии низких доз антибиотиков.

  • Стресс. Воспалительную реакцию могут запускать адреналин, кортизол и другие стрессовые гормоны, заявляют исследователи из Университета штата Огайо. Кроме того, хронический стресс тормозит ее «отключение», ослабляя иммунитет, т. е. замедляя борьбу с инфекциями.
  • Гиподинамия. Регулярная снижает в крови уровень СРБ.
  • Ненасыщенные жиры. Некоторые виды рыбы, орехи, льняное и рапсовое масла богаты омега-3-жирными кислотами, из которых образуются противовоспалительные эйкозаноиды. Большинству из нас надо потреблять побольше этих жиров и поменьше омега-6- жирных кислот (их много в сафлоровом, подсолнечном, кунжутном и кукурузном масле), идущих на образование других эйкозаноидов — стимулирующих воспаление. Доисторический человек потреблял примерно одинаковые дозы этих кислот, а сейчас последних в нашем меню в 11-30 раз больше, чем первых.
  • Трансжиры. Это так называемое гидрогенизированное растительное масло, т. е. в основном маргарин, на котором готовится покупная выпечка и прочий «фаст-фуд». Они мешают организму синтезировать и использовать противовоспалительные агенты.
  • Овощи и фрукты. Недостаток их в меню приводит к тому, что в рационе маловато сдерживающих воспалительный процесс антиоксидантов.
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